Is there reduced polyethylene wear and longer survival when using a mobile-bearing design in total knee replacement?

A meta-analysis of randomised and non-randomised controlled trials

Y. Zeng, B. Shen, J. Yang, Z. K. Zhou, P. D. Kang, F. X. Pei


The purpose of this study was to undertake a meta-analysis to determine whether there is lower polyethylene wear and longer survival when using mobile-bearing implants in total knee replacement when compared with fixed-bearing implants. Of 975 papers identified, 34 trials were eligible for data extraction and meta-analysis comprising 4754 patients (6861 knees). We found no statistically significant differences between the two designs in terms of the incidence of radiolucent lines, osteolysis, aseptic loosening or survival. There is thus currently no evidence to suggest that the use of mobile-bearing designs reduce polyethylene wear and prolong survival after total knee replacement.

Cite this article: Bone Joint J 2013;95-B:1057–63.


  • This research was funded by the China Health Ministry Program (201302007).

    No benefits in any form have been received or will be received from a commercial party related directly or indirectly to the subject of this article.

    This article was primary edited by D. Rowley and first-proof edited by J. Scott.

  • Received November 18, 2012.
  • Accepted April 25, 2013.
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